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For the 2025 school year, there are 15 public schools serving 9,018 students in Lancaster, SC (there are , serving 358 private students). 96% of all K-12 students in Lancaster, SC are educated in public schools (compared to the SC state average of 92%).

The top ranked public schools in Lancaster, SC are Indian Land High School, Buford High School and Buford Elementary School. Overall testing rank is based on a school's combined math and reading proficiency test score ranking.

Lancaster, SC public schools have an average math proficiency score of 40% (versus the South Carolina public school average of 43%), and reading proficiency score of 45% (versus the 52% statewide average). Schools in Lancaster have an average ranking of 6/10, which is in the top 50% of South Carolina public schools.

Minority enrollment is 52% of the student body (majority Black), which is less than the South Carolina public school average of 53% (majority Black).